Asthma: Basic Mechanisms and Clinical Management

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  2. 3rd Edition
  3. Asthma Basic Mechanisms Clinical
  4. Asthma and COPD: Basic Mechanisms and Clinical Management - Google книги

Rennard and Neil C. Editura : Academic Press. Distribuie pe:. Each chapter considers Asthma and COPD in side-by-side contrast and comparison — not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD Most extensive reference to primary literature on both Asthma and COPD in one source.

Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. At first it was a surprise to see that this impressive textbook covered both asthma and chronic obstructive pulmonary disease COPD in one volume.

Asthma and COPD: Basic Mechanisms and Clinical Management is edited and written by prominent individuals who have done everything possible in the past to convey the message that asthma and COPD are two different diseases: that they are characterised by different risk factors; have a different pathophysiology; are characterised by clinical phenotypes that are distinctly different; require different therapeutic strategies; and probably pose very different challenges to the health-care system.

Yet in this textbook they now provide a truly novel approach towards our understanding and perception of asthma and COPD Asthma and COPD provides a superb synthesis of the most up-to-date knowledge on obstructive airways diseases by leading experts in the field The description of basic mechanisms is a particularly strong feature, but the reader also finds excellent chapters on the pathogenic mechanisms of asthma and COPD, a description of risk factors and triggers, and a clinically useful description of the clinical assessment of these frequent conditions I hope that this book will become one of the major reference sources for information on asthma and COPD and that it might have the potential to serve a much wider medical community than respiratory textbooks usually do.


Rabe, The Lancet. Immunotherapies for Allergic Disease. Mims' Medical Microbiology and Immunology. Clinical Immunology. He has published over peer-review papers on asthma, COPD and related topics and has edited over 40 books. He is also amongst the top 50 most highly cited researchers in the world and has been the most highly cited clinical scientist in the UK and the most highly cited respiratory researcher in the world over the last 20 years.

3rd Edition

He was elected a Fellow of the Royal Society in , the first respiratory researcher for over years. He has co-edited several textbooks on asthma and COPD and published over peer-reviewed papers on asthma. His current research interests include corticosteroid insensitivity in smokers with asthma, biomarkers in asthma and COPD and assessment of novel treatments for asthma. Account Options Connexion. Asthma : Basic Mechanisms and Clinical Management. Peter J. Barnes , Ian W. Rodger , Neil C. Elsevier , 20 avr. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease.

The Third Edition has undergone radical revision and includes several new chapters. It retains the virtues of the previous volumes by bringing together all of the recent research findings by internationally recognized experts on the causative mechanisms of asthma, including in-depth clinical aspects and therapy.

The book presents an integrated approach toward the treatment of this disease with new concepts, changes in asthma management, and the development of new therapeutic agents. Asthma provides extensive references for researchers and clinicians who need to keep abreast of recent developments in this rapidly expanding field.

Comprehensive coverage of both basic science and clinical aspects of asthma Extensively referenced throughout. Page Mortality from asthma. Airway Pathology in Asthma. Enlargement of bronchial smooth muscle mass. Effects of posture and sleep on airway function. Extracellular matrix. Structural cells.

Asthma Basic Mechanisms Clinical

Transcription factors. Allergic bronchopulmonary aspergillosis. Occupational Asthma. Structure and Function.

Mast Cells and Basophils. Monocytes Macrophages and Dendritic Cells. Effects of glucocorticoids on monocytemacrophage function.

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Receptors and degranulation. Epithelial Cells. Adhesion molecules and the airway epithelium. Pathophysiology of Airway Mucus Secretion in Asthma. Consequences of airway mucus hypersecretion and hyperviscosity.

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Tracheobronchial Circulation. Adhesion Molecules. In vivo studies of adhesion receptor antagonists in models of allergic. Micro vascularEpithelial Exudation of Plasma.

Mucosal exudation of plasma in disease. Prostaglandins and Thromboxane.

Asthma and COPD: Basic Mechanisms and Clinical Management - Google книги

Inhibitory prostaglandins. Cysteinyl Leukotrienes. Chemokine receptors. Other Mediators of Asthma. Oxygen radicals. Therapeutic implications. Neural Control of Airway Function in Asthma.